Overview

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

Status:
Recruiting
Trial end date:
2030-08-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure
Phase:
Phase 3
Details
Lead Sponsor:
Ralf Hofheinz
Collaborators:
Deutsche Krebshilfe e.V., Bonn (Germany)
German Rectal Cancer Study Group
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Treatments:
Capecitabine
Fluorouracil
Folic Acid
Leucovorin
Levoleucovorin
Oxaliplatin