Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery

• Status: Recruiting
• Trial end date: 2021-01-20
• Target enrollment: 0
• Participant gender: All

Summary

There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection. Undertaking research in these groups of people may not be possible or ethical. However, it is likely that in situations where patients are at a higher risk of infection that preventative antibiotics may be beneficial, because infections in this group are likely to be more frequent and more difficult to treat To the best of knowledge, no adult study has compared the effects of single dose of Co-Amoxiclave and full oral course before or after dentoalveolar surgery. The current study has formally considered this comparison as a potential valuable trail for reducing the postoperative complications in adult patients who have had surgical removal of teeth under LA.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Taibah University
• Treatments: Acetaminophen; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Chlorhexidine; Chlorhexidine gluconate; Metronidazole

Criteria

Inclusion Criteria:

• Patient age from 16 to 70 yrs old

• Patient needs surgical teeth extraction (subject tooth will be removed using osteotomy by motorised drill).

Exclusion Criteria:

• Patients refusing the preoperative dose of oral co-amoxiclav, and unwilling to take part .

• Patients who are allergic to co-amoxiclve, amoxicillin or metronidazole

• Patient are on warfarin medication