The frequency of super-super obese who need immediate weight loss surgery is risen
continuously. For those patients a prior-to-surgery conditioning therapy is mandatory to gain
technical and physical operability. The exclusively well-established preliminary therapy so
far was the intragastric balloon, which takes 7 months of treatment time. Due to
life-threatening conditions of giant obese patients, who have been admitted to hospital, the
investigators were forced to develop a more prompt acting conditioning therapy to bring those
individuals in a short run to an improved and "fit-for-surgery" state. In such an impasse the
investigators combine Liraglutide with its well-known weight-loss effect with a leucine-based
amino acid infusion that is generally used for patients with liver insufficiency, in
expectance of an additional weight loss and liver reduction effect.