Preoperative Chemoradiotherapy vs. Chemotherapy Alone in NSCLC Patients
Status:
Active, not recruiting
Trial end date:
2037-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel and cisplatin, use different ways to
stop tumor cells from dividing so they stop growing or die. Radiation therapy uses
high-energy x-rays to damage tumor cells. Giving chemotherapy with radiation therapy before
surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be
removed. It is not yet known if chemotherapy plus radiation therapy is more effective than
chemotherapy alone before surgery in treating non-small cell lung cancer.
PURPOSE: This randomized phase III trial is studying docetaxel and cisplatin with or without
radiation therapy to see how well they work when given before surgery in treating patients
with stage IIIA non-small cell lung cancer that has spread to lymph nodes in the chest.