Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat

• Status: Recruiting
• Trial end date: 2022-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Post-operative sore throat (POST) following General Anesthesia with endotracheal is a common symptom and drains resources. The researchers will compare preoperative gargling of Asprine and Benzydamine HCL to study comparative effects on intensity and duration of POST. Data collected as such will be analyzed to reach at a conclusion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rehman Medical Institute - RMI
• Treatments: Aspirin; Benzydamine

Criteria

Inclusion Criteria:

• Patients of American Society of Anesthesiologists Class 1 and 2 (ASA 1 and 2) scheduled for surgery not involving oral cavity and expected to finish in less than an hour will be included in the study.

• Patients of 18- 50 years of age will be included.

• Patients of Mallampati class 1 and 2 will be selected, as these have easy intubation predicted.

• Patients qualifying for easy intubation (prediction based on mouth opening, neck mobility etc.) will be selected.

• Patients in supine intraoperative position will be included

Exclusion Criteria:

• Patients who are unable to gargle properly.

• Patients who require more than 2 attempts at intubation.

• Patients of Cormack-Lehane Grade 3 and 4 on direct laryngoscopy (multiple intubating attempts may be required).

• Patients requiring oral cavity instrumentation e.g. N/G tube placement, oral or laryngeal surgeries including tonsillectomies

• Patients whose head are frequently turned with ETT placed in.

• Patients whose surgery is prolonged beyond 1 hour.

• Patients who require postoperative mechanical ventilation.