Preop Dexmedetomidine Attenuates Haemodynamic Responses to Hydrodissection
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Percutaneous tunnelling (hydrodissection) in the neck and anterior chest in patients
undergoing robotic thyroidectomy leads to significant haemodynamic responses such as
increases in blood pressure and heart rate. The investigators evaluated whether a single
preoperative dexmedetomidine injection attenuated the haemodynamic responses to
hydrodissection by reducing the half-maximal effective concentration (EC50) of remifentanil
needed to maintain haemodynamic stability during hydrodissection.