OBJECTIVE:Purpose of this study is to set forth the sedative efficacy and effects on early
period cognitive functions of two premedication drugs used for ERCP (Endoscopic retrograde
cholangiopancreatography) METHODS:This randomized and double blind study was performed with
forty (18-70 of age) ASA I-III risk group patients for who elective ERCP was planned.
Cognitive functions of patients were determined by mini-mental test (MMT). 0.5 mg/kg
midazolam or 1mg/kg tramadol drop was administered orally before intervention to patients who
were randomly divided into two premedication groups.
Vital signs,BIS (Bispectral index), mRSS (modified Ramsay Sedation scale), NRS (numeric
rating scale ) was evaluated. If MMT (mini-mental test) was ≤ 23 at 60th minute it was
considered as cognitive impairment. Recovery period, post-procedure state of cognitive
function at 60th minute were recorded.