Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Objectives: To compare the safety and efficacy of oral atenolol versus oral metoprolol as a
premedication for controlled hypotensive anesthesia during nasal surgeries.
Background: Mucosal bleeding is the most frequent complication with nasal surgeries, as it
interferes with the optimal visualization of the intranasal anatomy, increases operation
time, and consequently increases blood loss. There are several pharmacological and
non-pharmacological techniques for the appropriate control of intraoperative bleeding.
Patients and Methods: This was a prospective, randomized, double-blind, phase four,
comparative clinical trial; carried out on 60 patients, who were candidates for nasal
surgeries under general anesthesia at our hospital. Patients were randomly allocated into two
equal groups; group A, received oral atenolol, and group M, received oral metoprolol.