Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis
Status:
Completed
Trial end date:
2010-03-01
Target enrollment:
Participant gender:
Summary
Mouthwash based on medicinal plants and propolis can be easily found in the Brazilian market
even if it has not been tested in reliable clinical trials on its efficacy or possible
unpleasant side effects like the ones which alter the hard and soft oral tissues. The aim of
this study was to obtain preliminary evidence of efficacy of an alcohol-free mouthwash
containing 5% green propolis (MGP 5%) on the control of plaque and gingivitis. Were chosen
twenty-five subjects that are UFMG employees and individuals who would begin treatment on an
extension project called Supportive Periodontal Therapy at the Faculty of Dentistry of
Federal University of Minas Gerais, Belo Horizonte, from August to December 2009. The
subjects went through a dental prophylaxis before starting rinse. They were then instructed
to rinse twice a day for a minute, immediately after brushing (morning and night), using the
10 ml of the MGP 5%. After 45 and 90 days using the product the individuals returned for a
clinical evaluation which considered changes in the soft and hard oral tissues and involved
collecting plaque and gingivitis indexes. On their last appointment the subjects answered a
questionnaire about their level of appreciation and acceptability of the mouthwash.
Compliance with the treatment was also evaluated through an attendance form. For the
statistic analysis we used BioEstat 4.0 and Excel 2007.
Phase:
Phase 2
Details
Lead Sponsor:
Federal University of Minas Gerais
Collaborators:
Conselho Nacional de Desenvolvimento Científico e Tecnológico Fundação de Amparo à Pesquisa do estado de Minas Gerais