Pregnant Women Taking Lamictal for Bipolar Disorder
Status:
Active, not recruiting
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
This study seeks to examine how the dose of lamotrigine (Lamictal) should be adjusted during
pregnancy for women with Bipolar Disorder. The investigators predict that the concentration
of Lamictal in women's blood will decrease during pregnancy, and increase after postpartum.
Because the concentration of the medication is likely to decrease during pregnancy, it is
important for doctors to know how much they should increase a patient's dose in order to
prevent worsening of Bipolar symptoms. In this study, the investigators will ask that
participants complete up to five overnight visits to our clinical research unit where their
blood will be drawn every couple of hours, through an IV catheter, to measure how the
concentration of lamotrigine (Lamictal) changes over time. Participants will be compensated
for their time.