Pregabalin on Interleukin-6 Levels in Living Donor Kidney
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Pregabalin, a ligand for alfa2delta subunits of voltage-gated calcium channels, has been
shown to be an effective adjuvant therapy for acute postoperative pain, by inhibiting central
sensitization. The IL-6, is detectable 60 minutes after surgical incision, persisting for
until 10 days, with maximal plasmatic level in 4 and 6 hours. The objective of this study is
evaluating the analgesic effect of pregabalin and its repercussion on serum levels of IL6.