RATIONALE: Pregabalin may help relieve hot flashes in women with a history of breast cancer
or those who have no history and do not wish to take estrogen therapy for fear of increased
risk of breast cancer. It is not yet known what dose of pregabalin may be more effective in
treating hot flashes.
PURPOSE: This is a randomized phase III trial to determine the efficacy of two doses of
pregabalin, in comparison to placebo, in the prevention of hot flashes.