Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate
markers postoperative pain rating scores and postoperative opioid consumption while improving
the quality of recovery following breast cancer surgery compared to placebo. The primary
outcome will be postoperative pain, measured by a NRS and the quality of recovery score (QoR)
in the first 24h postoperative period. Do women undergoing breast cancer surgery with general
anesthesia and receiving pregabalin prior to their surgery and 12 hours later have lower NRS
and a greater QoR score in the first 24 hours after their surgery than those women who
received placebo?