Overview

Pregabalin and Remifentanil - Analgesia and Ventilation

Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
0
Participant gender:
All
Summary
In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Oslo University Hospital
Treatments:
Pregabalin
Remifentanil
Criteria
Inclusion Criteria:

- Healthy volunteers,

- > 18 yrs < 55 yrs,

- negative pregnancy test

Exclusion Criteria:

- Pregnancy,

- nursing,

- known heart-, lung- or liver disease,

- kidney failure/peptic ulcers,

- use of liver enzyme-inducing medications,

- known allergy against the medications used in the trial,

- use of psychotropic drugs, analgesics or alcohol used the last 24 hours before the
trial,

- body weight > 100 kg or 30% deviation from normal weight,

- participant in other studies during the last 2 months,

- individuals who do not master Norwegian language