Pregabalin and Radicular Pain Study (PARPS)

• Status: Completed
• Trial end date: 2010-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to investigate the effectiveness of pregabalin (Lyrica) on nerve pain caused by degenerative neck problems. Pregabalin is a new drug registered for use in nerve pain worldwide

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Singapore General Hospital
• Collaborator: Pfizer
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• Clinical & MRI, or electrophysiological evidence of pain due to radiculopathy

• Patients with CS and CSR or CSM with neuropathic pain due to the above in the neck and upper limbs or lower limbs (including dysesthesia, paresthesia, hyperalgesia).

Exclusion Criteria:

• Diabetic neuropathy or other underlying neuropathic conditions

• Contraindications and allergy to pregabalin

• Previously treated with gabapentin in the last 8 weeks

• Pregnant or breast feeding

• History of renal impairment

• History of other causes of neuropathic pain