Pregabalin Premedication for Knee Arthroscopy

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Outpatient arthroscopic knee surgery can be performed with general or regional anesthesia. Recent data suggest that spinal and epidural anesthesia require longer discharge times than the newer shorter-acting general anesthetic drugs. Ideal premedication drug should relieve anxiety, produce amnesia and sedation, decrease secretions, prevent nausea and vomiting, have dose sparing effect on the anaesthetic drugs, and suppress pressor response to laryngoscopy and intubation. Recently, gabapentin and pregabalin were suggested as pre-operative drugs to decrease anxiety, stress response to laryngoscopy and post operative pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• Patients scheduled for elective knee arthroscopy.

• Patients aged between 21 and 50 years old.

• Patients with American Society of Anaesthesiologists physical status I or II.

Exclusion Criteria:

• Patients with known allergy to any drug used in the study.

• Patients with chronic use of analgesics and/or sedatives.

• Patients with sleep apnea syndrome.

• Patients with renal or hepatic dysfunction.

• Patients with psychiatric disorders.