Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Status:
Completed
Trial end date:
2019-04-30
Target enrollment:
Participant gender:
Summary
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension
during general anesthesia. That is beneficial to limit the intraoperative blood loss and
transfusions and improves surgical field. Deliberate hypotension could be achieved via
various medications but mostly associated with significant side effects. Pregabalin
effectively augmented hypotensive anesthesia. The hypothesis is that Pregabalin 150 mg single
preoperative dose may augment intraoperative deliberate hypotension that will be reflected on
blood loss and nitroglycerin consumption.