The aims of this study was to compare analgesic efficacy of preoperative administration of
etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior
cruciate ligament reconstruction. One hundred and two patients diagnosed as anterior cruciate
ligament injury will randomized into 3 groups using opaque envelope. Both patients and
surgeon were blinded to the allocation. All of the patients will be operated by one
orthopaedic surgeon under regional anesthesia. Each group will be given either etoricoxib 120
mg., celecoxib 400 mg., or placebo 1 hour prior to operative incision. Post-operative pain
intensity, time to first dose of analgesic requirement and numbers of analgesic used for
rescue pain control and adverse events will be recorded periodically to 48 hours after
surgery.