Preemptive Analgesia for Post Tonsillectomy Pain With IV Morphine in Children
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
In this double blind study, after taking an informed consent, 60 children aged between 7 and
12 years old assigned for tonsillectomy with or without adenoidectomy will be randomly
divided into three groups. The first group 30 children will receive 0.025 mg/kg midazolam IV
followed by 0.1 mg/kg morphine as a premedication 20 to 30 min before surgical incision. In
the second group30 children who will receive the same dose of midazolam followed by saline
premedication. All groups will be compared for pain score using visual analog scale (VAS)
after recovery and hourly for 8 hours and during first drinking. Heart rate (HR), blood
pressure and peripheral oxygen saturation (SPO2) will be recorded before premedication, every
10 min after premedication then every 5 min during and after anesthesia. 6 point sedation
score and 4 points behavioral score will be monitored every 5 min after sedation. Four-point
wake-up score will be recorded every 5 min. Time of first analgesic requirement and total
morphine consumption during the first post-operative 8 hours will be recorded.