Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

• Status: Not yet recruiting
• Trial end date: 2023-04-30
• Target enrollment: 0
• Participant gender: All

Summary

This is a double-blinded randomized controlled trial aims to evaluate the effect of preemptive analgetic combination of celecoxib and pregabalin to acute pain after total hip arthroplasty. This study will be conducted in Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from October 2022 to April 2023. The subject of this study is adult patient who will be performed total hip arthroplasty.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Indonesia University
• Treatments: Celecoxib; Pregabalin

Criteria

Inclusion Criteria:

1. Patients >18 years old

2. Patients who come to the RSCM Orthopedic Polyclinic

3. Patients undergoing THA operasi surgery

4. Patients with Primary and Secondary Pelvic Osteoarthritis

5. The patient is taking anti-pain and anti-inflammatory drugs regularly

Exclusion Criteria:

1. Patients with mental disorders

2. Patients with a history of renal impairment

3. Pelvic arthritis patients due to rheumatoid arthritis or infection

4. Patients with diabetes and obesity

5. Allergy to non-steroidal inflammatory drugs

6. Asthma history

7. Coagulation disorders