Prednisone for Heart Failure Patients With Hyperuricemia
Status:
Completed
Trial end date:
2018-08-31
Target enrollment:
Participant gender:
Summary
Hyperuricemia is a very common finding in patients with heart failure. It is usually related
to diuretic use and deteriorated renal function. The recently evidence showed that prednisone
and allopurinol may have similar effect on uric acid (UA) lowering in symptomatic heart
failure patients with hyperuricemia, but prednisone may be superior over allopurinol in renal
function improvement. Thus the investigators design this randomized head to head study to
test their hypothesis that prednisone is superior over allopurinol in renal function
improvement despite their similar effect on UA lowering in heart failure patients with
hyperuricemia.