Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
This is part 2 of the #NCT01618240 under the same IRB protocol #2010P001919. The primary
objective of this study is to examine factors that are related to sleep-disordered breathing
and upper airway patency in critically ill patients who have been recently mechanically
ventilated. Our primary hypothesize is that sedatives and neuromuscular blocking agents given
in the ICU prior to extubation and during the first night following extubation are associated
with sleep-disordered breathing. The secondary hypotheses are that duration of mechanical
ventilation, BMI, and muscle strength are associated with sleep-disordered breathing during
the night after extubation.
The secondary objective is to evaluate if sleep-disordered breathing in the ICU can be
predicted by standard pulmonary function testing in the ICU.