Overview

Predictors of Cognitive Outcomes in Geriatric Depression

Status:
Recruiting
Trial end date:
2026-06-30
Target enrollment:
Participant gender:
Summary
This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging. Understanding how effects of stress in older depressed adults, as well as factors that might minimize those effects, lead to particular mood and cognitive outcomes will inform future development of novel prevention strategies.
Phase:
Phase 4
Details
Lead Sponsor:
David Steffens
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Bupropion
Desvenlafaxine Succinate
Sertraline