Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests
Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
This is a single site, prospective, cross-sectional, controlled clinical study on a total of
66 subjects. The subjects are divided into two groups: Hypertonic Saline Non-Responders (33
subjects) and Hypertonic Saline Responders (33 subjects). After completion of questionnaires,
the subjects will undergo Dry Eye Disease testing and functional nerve testing. Subjects who
qualify will be dispensed 4 weeks of preservative free artificial tears and instructed to
instill one drop into each eye twice daily. Subjects will return for a follow up visit 4
weeks later (± 4 days), during which subjects will complete the questionnaires again and the
Dry Eye Disease tests and functional nerve tests will be repeated.