Overview
Preconditioning With Sevoflurane and Propofol in Patients Undergoing Minimally Invasive Mitral Valve Surgery
Status:
Unknown status
Unknown status
Trial end date:
2016-09-01
2016-09-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The main aim of this study is to compare markers of cardiac injury (Troponin I), inflammatory response and platelets function during minimally invasive mitral valve repair or replacement (MIMV) via right mini-thoracotomy in two standard anaesthetic regimes (sevo \propofol)Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Fondazione Toscana Gabriele MonasterioTreatments:
Propofol
Sevoflurane
Criteria
Inclusion Criteria:1. Age ≥18
2. Patients undergoing elective (or urgent) first-time minimal invasive mitral valve
surgery.
Exclusion Criteria:
1. Cardiogenic shock or cardiac arrest, emergent CABG
2. Renal failure (with a GFR < 30 ml/min/1.73m2),
3. Glibenclamide or nicorandil (as these medications may interfere with VC)
4. Pregnancy
5. Known intolerance/allergy to sevoflurane or propofol