Overview

Precision Dosing of Beta-lactam Antibiotics in Critically Ill Children

Status:
NOT_YET_RECRUITING
Trial end date:
2027-10-01
Target enrollment:
Participant gender:
Summary
The overall objective of this study is to investigate the impact of early model-informed precision dosing (MIPD) on target attainment of three beta-lactam antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam and meropenem) in critically ill children. This evaluation includes a comparison with the more standard approach on clinical and patient-oriented measures.
Phase:
PHASE4
Details
Lead Sponsor:
University Hospital, Ghent
Treatments:
Amoxicillin-Potassium Clavulanate Combination
Meropenem
Monobactams
Piperacillin, Tazobactam Drug Combination