Pre-operative Olanzapine as Prophylactic Antiemetic in Oncologic Patients
Status:
Completed
Trial end date:
2021-02-10
Target enrollment:
Participant gender:
Summary
Olanzapine has been used as prophylactic antiemetic for chemotherapy induced nausea and
vomiting.
The project aims to evaluate the efficacy of olanzapine in combination with ondansetron and
dexamethasone in patients at high risk of postoperative nausea and vomiting, with previous
history of nausea and vomiting induced by prior chemotherapy, submitted to medium and large
surgery.