Overview

Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures

Status:
Active, not recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative skin preparation with an antiseptic solution. The available solutions kill bacteria and decrease the quantity of native skin flora, thereby decreasing surgical site infection (SSI). While there is extensive guidance on specific procedures for prophylactic antibiotic use and standards for sterile technique, the evidence regarding the choice of antiseptic skin preparation solution is very limited for open fracture surgery.
Phase:
Phase 4
Details
Lead Sponsor:
University of Maryland
University of Maryland, Baltimore
Collaborators:
McMaster University
United States Department of Defense
Treatments:
Anti-Infective Agents, Local
Cadexomer iodine
Chlorhexidine
Chlorhexidine gluconate
Iodine
Pharmaceutical Solutions
Povidone
Povidone-Iodine