Overview

Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain

Status:
Recruiting
Trial end date:
2023-01-01
Target enrollment:
0
Participant gender:
All
Summary
Postcraniotomy pain remains a common phenomenon in the neurosurgery field. Managements for postcraniotomy pain are to be standardised and optimized. In the proposed study, the investigators aim to provide a novel regional non-invasive prophylactic strategy for postcraniotomy pain by utilizing Lidocaine 5% plaster.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Beijing Tiantan Hospital
Treatments:
Lidocaine
Criteria
Inclusion Criteria:

- Age of 18 or older

- American Society of Anesthesiologists status I or II

- Registered for elective craniotomy

- Informed consent for participation in the trial

Exclusion Criteria:

- Allergy to lidocaine or the hydrogel plaster

- Chronic headache, craniofacial pain or neuralgia

- Glasgow Coma Scale less than 15

- Current or previous cardiovascular or cerebrovascular accident

- Expected delayed recovery or extubation

- Uncontrolled arrhythmia

- History of intracranial operation

- Emergency or revision craniotomy

- Mental illness, psychiatric drug use or alcohol abuse

- Failure to understand the use of a 100 mm VAS or the PCA