Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain.
Status:
Not yet recruiting
Trial end date:
2023-03-01
Target enrollment:
Participant gender:
Summary
We propose a double-blind randomized controlled trial to evaluate the effect of intravenously
administered morphine at surgery conclusion on acute postoperative pain in patients
recovering from craniotomy surgery. Participating adults having craniotomy surgery will be
randomized in a 1:1 ratio to intraoperative intravenous administration of 0.08 mg/kg morphine
at dura closure, or a matching placebo.