Pre-emptive Analgesics in Orthodontic Treatment

• Status: Completed
• Trial end date: 2017-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to determine if the preemptive use of a combination of acetaminophen and ibuprofen is more effective in reducing pain following orthodontic tooth movement when compared to the use of acetaminophen and ibuprofen alone.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Washington
• Treatments: Acetaminophen; Analgesics; Ibuprofen

Criteria

Inclusion Criteria:

-Orthodontic patient presenting for orthodontic treatment

Exclusion Criteria:

• History of taking an analgesic in the past six hours

• Hypersensitivity to ibuprofen or acetaminophen

• Aspirin-sensitive asthma

• Renal or liver impairment

• History of GI bleeding or ulcers

• Cardiovascular disease, recent myocardial infarction, heart failure, or coronary artery bypass graft surgery

• Currently taking antibiotics or other medications for a chronic systemic disease

• Bleeding disorder

• Pregnant or nursing