Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance
Status:
Terminated
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
The purposes of this study are:
- to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for
combat stress-related nightmares, sleep disturbance and overall function in recently
combat-exposed returnees from Operation Iraqi Freedom (OIF) and Operation Enduring
Freedom (OEF).
- to evaluate the effects of the selective serotonin reuptake inhibitor (SSRI) paroxetine
on behavioral symptoms and overall function in this population.
Phase:
N/A
Details
Lead Sponsor:
Seattle Institute for Biomedical and Clinical Research
Collaborators:
United States Department of Defense VA Puget Sound Health Care System