Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
Status:
Recruiting
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
During end-stage kidney disease, clinical guidelines suggest reducing elevated phosphate
levels in the blood. However, the effect of lowering blood phosphate levels on important
patient-centred outcomes has never been tested. This trial will evaluate whether compared to
high levels, lowering blood phosphate levels would reduce death or major events due to heart
disease, improve physical health, and be cost-effective.
Phase:
N/A
Details
Lead Sponsor:
The University of Queensland
Collaborators:
Applied Health Research Centre Cambridge University Hospitals NHS Foundation Trust National Health and Medical Research Council, Australia University of Otago