Overview

Ppar-Gamma EliminAtes Restenosis Longevity Study: PEARLS

Status:
Terminated
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
The primary objective of this clinical trial is to assess the efficacy of rosiglitazone on bare metal stent (BMS) in-stent restenosis measured as late lumen loss in patients with metabolic syndrome. The secondary parameter for evaluation of efficacy is binary restenosis. The tertiary objective will be to assess the effect of rosiglitazone on major cardiac events (MACE; death, MI, CABG, and target vessel revascularization). The occurrence of in-stent restenosis for patients with metabolic syndrome who receive a DES in a non-target lesion will be assessed angiographically at 9 months.
Phase:
Phase 3
Details
Lead Sponsor:
Medstar Health Research Institute
Collaborator:
GlaxoSmithKline
Treatments:
Rosiglitazone