Postoperative Pain Control in Septum and Sinus Surgery

• Status: Recruiting
• Trial end date: 2023-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients. Participants will be randomized like a flip of a coin to either the standard of care pain treatment of acetaminophen 325 mg as needed for pain plus opiates (acetaminophen/hydrocodone) as needed for breakthrough pain; OR to the study arm of acetaminophen 650 mg every 6 hours plus opiates (Oxycodone)as needed for breakthrough pain.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: William Beaumont Hospitals
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Hydrocodone; Oxycodone

Criteria

Inclusion Criteria:

• Undergoing primary sinus surgery, primary septum surgery, or primary sinus/septum surgery

• 18 years of age or older

• Male or female

• No known allergies to or contraindications to the use of acetaminophen, hydrocodone, or oxycodone

• Patients discharged to home after surgery

Exclusion Criteria:

• Undergoing revision sinus, septum, or sinus/septum surgery

• Younger than 18 years old

• Allergy or contraindication to acetaminophen, hydrocodone, or oxycodone

• Patients admitted to the hospital postoperatively for airway monitoring