Postoperative Pain After Orthopedic Surgery: Does it Help to Give Fentanyl Before Start of Remifentanil Based Anesthesia?

• Status: Completed
• Trial end date: 2006-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this trial is to examine the possibility that fentanyl 1,5 µgr/kg given intravenously (i.v.) before the start of remifentanil infusion for anesthesia gives less development of tolerance/hyperalgesia postoperative than fentanyl given at the end of surgery (the traditional method).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ullevaal University Hospital
• Collaborator: University of Oslo
• Treatments: Fentanyl; Remifentanil

Criteria

Inclusion Criteria:

• Women and men > 18 years.

• Informed consent.

• Elective day-orthopedic surgery: damage to anterior cruciate ligament and/or posterior cruciate ligament with or without medial collateral ligament.

Exclusion Criteria:

• Patients who use nonsteroidal anti-inflammatory drugs (NSAID's) or are allergic to NSAID's.

• Patients using steroids, anti-emetics, drugs or opioids.