Overview

Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion

Status:
Terminated
Trial end date:
2018-01-11
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this project is to study the effects of preoperative followed by scheduled intravenous acetaminophen on pain control for 24 hours postoperatively after minimally invasive 1 or 2 level transforaminal lumbar interbody fusion.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Texas Tech University Health Sciences Center
Treatments:
Acetaminophen
Criteria
Inclusion Criteria:

- Age > 18 years old

- Being scheduled to have elective primary minimally invasive 1 or 2 level
transforaminal lumbar laminectomy interbody fusion

- ASA I, II, or III

- Informed consent form signed

Exclusion Criteria:

- Anyone weighing less than 50kg (as this would require a dosing change).

- Hypersensitivity or contraindication to intravenous acetaminophen or opioids

- Allergy to Methocarbamol; morphine sulfate, sevoflourane, or fentanyl

- Impairment of liver function-- defined as the inability to receive intravenous
acetaminophen without dose adjustment as determined by the investigator; or history of
chronic liver disease defined as history of hepatitis of any kind as recorded in the
patient's chart

- Mental retardation recorded as a diagnosis in the patient's chart

- History of chronic pain (defined as currently receiving treatment from a specialist
for pain)

- History of pain recalcitrant to intravenous morphine

- Impaired kidney function (defined as creatinine > 1.5)

- Anyone who is not a candidate for general anesthesia or any other portion of the
investigator's standard of