Postoperative New-onset Atrial Fibrillation in Cardiac Surgery: DECS-PNAF Project
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
The DExamethasone for Cardiac Surgery - Postoperative New-onset Atrial Fibrillation
(DECS-PNAF) project described in this protocol aims to elucidate how corticosteroids protect
cardiac surgical patients from Postoperative New-onset Atrial Fibrillation (PNAF). Patients
will be randomized to receive either a single high dose of dexamethasone or a placebo.
Continuous ECG-monitoring, echocardiography and biochemical and genomic analyses will be used
to investigate the mechanisms responsible for the known protective effect of corticosteroids
in the development of PNAF.