Overview

Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery

Status:
Unknown status
Trial end date:
2009-07-01
Target enrollment:
0
Participant gender:
All
Summary
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia. The purpose of this study is to examine the effectiveness of ketamine as a preemptive analgesic as previous studies have shown the involvement of N-methyl-D-Aspartate (NMDA) receptor in neuroplasticity.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Tehran University of Medical Sciences
Treatments:
Anesthetics
Ketamine
Criteria
Inclusion Criteria:

- Children aged < = 12 years

- Children scheduled for elective orthopedic surgery with caudal block

- ASA score < = 3

Exclusion Criteria:

- Contraindication for caudal block such as vertebral defect or infection at the site of
block

- Disagreement of parents

- Patient's age > 12 years

- ASA score > = 4