Post-operative or Early Salvage XRT and ADT for High Risk PCa
Status:
Terminated
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Conformal radiation therapy uses a 3-dimensional (3-D) image of the tumor to help
focus thin beams of radiation directly on the tumor. Giving conformal external-beam radiation
therapy in higher doses over a shorter period of time may kill more tumor cells and have
fewer side effects. Androgens can cause the growth of prostate cancer cells. Hormone therapy,
such as leuprolide acetate, may lessen the amount of androgens made by the body. It is not
yet known whether radiation therapy is more effective when given together with or without
hormone therapy in treating patients with prostate cancer who have undergone surgery.
PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it
works compared with radiation therapy given together with hormone therapy in treating
patients who have undergone surgery for stage I, stage II, or stage III prostate cancer.
Phase:
Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC