Overview

Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies

Status:
Recruiting
Trial end date:
2026-11-01
Target enrollment:
Participant gender:
Summary
This study aims to evaluate the clinical efficacy of cyclophosphamide in patients receiving a bone marrow graft from a matched unrelated donor in overall survival, progression free survival and cumulative incidence of acute and chronic GvHD. Thirty patients will receive cyclophosphamide while twenty patients will receive antihuman T-lymphocyte immune globulin (ATG).
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Hospital Israelita Albert Einstein
Treatments:
Calcineurin Inhibitors
Cyclophosphamide
Thymoglobulin