Overview

Post-Transplant Bortezomib and High Dose Cyclophosphamide as Graft-Versus-Host Disease (GVHD) Prophylaxis

Status:
Unknown status
Trial end date:
2018-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if Bortezomib, known commercially as Velcade is safe and tolerated at different dose levels (amounts) with high dose Cyclophosphamide to be used as graft versus host disease prevention after reduced-intensity allogeneic hematopoietic stem cell transplantation.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Spectrum Health Hospitals
Collaborator:
Millennium Pharmaceuticals, Inc.
Treatments:
Bortezomib
Cyclophosphamide