Post Kidney Transplant Nocturnal Hypertension Prevalence and Management Study
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Hypertension (HTN) affects up to 75% of kidney transplant recipients and is associated with
premature death. Nocturnal HTN is a common complication of ongoing essential HTN or a
secondary cause of HTN. Both the non dipping of systolic blood pressure (SBP) at night time
and the reverse dipping is associated with increased target organ damage and adverse
cardiovascular outcomes and possibly allograft survival. Treatment of Nocturnal HTN is
critical. Chronotherapy has been shown to be effective in halting progression in patients
with diabetic nephropathy and chronic kidney disease. There is not enough data on prevalence
and management of nocturnal HTN in transplant patients, which is the object of this study.