Overview

Post Burn Pruritus Study in Patients Undergoing Wound Healing

Status:
Completed
Trial end date:
2006-05-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to see if a drug called ondansetron (Zofran) controls itching from healing burn wounds as well or better than the usual drug used, diphenhydramine (Benadryl).
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
United States Army Institute of Surgical Research
Treatments:
Diphenhydramine
Ondansetron
Promethazine
Criteria
Inclusion Criteria:

- Males or females; 18 years or older.

- Seen in the United States Army Institute of Surgical Research (USAISR) Burn Clinic
with healing burn wounds of any percent (%) of total body surface area (TBSA) causing
pruritus

- Stable medical condition

- Negative pregnancy test and not nursing

- Able to indicate status of pruritus on a numeric scale

- Able to understand and read English

Exclusion Criteria:

- Unstable medical condition as determined by attending burn surgeon

- Prisoner

- History of allergic reaction to serotonin inhibitors or diphenhydramine

- Pregnant or lactating

- Unable to verbalize pruritus intensity scale

- Unable to understand or read English