Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI

• Status: Terminated
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Children who receive general anesthesia may become agitated (emergence delirium) in the recovery period. This occurs more often after inhalational anesthetics, particularly sevoflurane and desflurane than after propofol. However, agitation after anesthesia in children may be difficult to distinguish from pain; accordingly studies are ideally designed during MRI to obviate the contribution of pain during emergence. Airway complications have been reported after LMA and isoflurane more commonly than with IV propofol and nasal prongs. Whether the airway complications were due to the LMA or the isoflurane was unclear. Therefore, this study was designed to study the incidence of 1. agitation after sevoflurane compared with IV propofol and 2. airway complications after LMA or nasal prongs.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: State University of New York at Buffalo
• Treatments: Anesthetics; Isoflurane; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• Age 2-12yrs,

• ASA Class I-II,

• Fasting,

• Unmedicated,

• Elective MRI scan

Exclusion Criteria:

• Cognitive impairment,

• On psychotropic medications,

• Taking multiple (>2) antiepileptic medications,

• Requiring endotracheal intubation for GA