Overview Positron Emission Tomography (PET) Study Status: Completed Trial end date: 2009-08-01 Target enrollment: Participant gender: Summary The primary purpose is to study the occupancy at the α4β2 neuronal nicotinic receptor's (NNRs) and to determine the relation between plasma concentration of AZD1446 and the occupancy at α4β2 NNRs. Phase: Phase 1 Details Lead Sponsor: AstraZeneca