Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and Berberine
Status:
Unknown status
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder affecting almost4%-7% of the
female population of reproductive age. Its heterogeneity is characterized by a wide spectrum
of features, including ovulatory dysfunction and infertility, hyperandrogenism,
hyperinsulinemia, insulin resistance (IR), and progression to type 2 diabetes.Since the Ming
Dynasty in China,PCOS has been defined as "phlegm and wetness"infertility in traditional
Chinese medicine ,namely "metabolic infertility".Chinese herbs have been used to treat PCOS
for thousands of years with good effects.Berberine has also been used for diabetic patients
in traditional Chinese medicine for hundreds of years. Recent studies have reported its
effects on hyperglycemia and dyslipidemia.The purpose of this study is to determine whether
Letrozole combined with berberine are effective in the treatment of infertile PCOS patients.
Phase:
N/A
Details
Lead Sponsor:
Heilongjiang University of Chinese Medicine
Collaborator:
Ministry of Science and Technology of the People´s Republic of China