Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate
Status:
Terminated
Trial end date:
2010-07-01
Target enrollment:
Participant gender:
Summary
The purposes of this study are: to determine the feasibility of administering adjuvant
cisplatin plus ALIMTA to patients who undergo surgery with heated cisplatin during surgery;
to determine the effects (good and bad) of this combined modality approach in patients with
mesothelioma; to evaluate cisplatin effects by determining where it goes and how it is
excreted in the body from the collection of tissues and cisplatin samples; to collect and
analyze discarded samples of mesothelioma tumor during surgery to help determine the genetic
make-up of the disease.