Plerixafor and Filgrastim Following Cyclophosphamide for Stem Cell Mobilization in Patients With Multiple Myeloma
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: There are different methods of stem cell mobilization, such as using
colony-stimulating factors alone or following chemotherapy priming. More recently, the
combination of plerixafor and colony-stimulating factors has been shown to enhance stem cell
mobilization. This study will assess whether the combination of plerixafor and Granulocyte
Colony-Stimulating Factor (G-CSF) is effective following chemotherapy mobilization with
cyclophosphamide.
PURPOSE: To assess the safety, tolerability, and best dose of intravenous plerixafor
following cyclophosphamide priming.
Phase:
Phase 1
Details
Lead Sponsor:
City of Hope Medical Center
Treatments:
Cyclophosphamide JM 3100 Lenograstim Plerixafor Sargramostim