Platelet Rich Plasma in Carpal Tunnel Syndrome

• Status: Unknown status
• Trial end date: 2020-01-30
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to evaluate the effect of local platelet rich plasma injection therapy in patients with mild to moderate idiopathic carpal tunnel syndrome (CTS) with clinical and electrophysiological parameters. Also the effect of platelet rich plasma and local steroid injection will be compared.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Baskent University
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone dipropionate, betamethasone sodium phosphate drug combination; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate

Criteria

Inclusion Criteria:

• female patient 25-75 years old

• Symptoms consistent with carpal tunnel syndrome for at least 3 months

• Clinical and electrophysiological diagnosis of mild to moderate carpal tunnel syndrome

• Written informed consent obtained

Exclusion Criteria:

• Electrophysiological diagnosis of proximal median nerve neuropathy, cervical radiculopathy, brachial plexopathy, thoracic outlet syndrome

• Those with a past medical history of diabetes mellitus, hypothyroidism, pregnancy, chronic inflammatory rheumatic disease, renal insufficiency which may predispose to CTS

• Patients with a history of wrist surgery or radius distal tip fracture

• Patients who underwent carpal tunnel local steroid injection within the previous 3 months

• Patients with a cardiac pacemaker

• History of hematological disease (coagulopathy) or patients receiving anticoagulant or antiaggregant therapy

• Severe cardiovascular disease

• Infection, immunosuppression

• Patients using non-steroidal anti-inflammatory drugs up to 5 days before PRP injection patients with hemoglobin levels below 11 and platelet levels below 150,000